· Crush Injuries
· Heat intolerance
· Heatstroke
· Ischemia or necrosis of the muscles (as may occur with arterial occlusion, deep venous thrombosis, or other conditions)
· Low phosphate levels
· Seizures
· Severe exertion such as marathon running or calisthenics
· Shaking chills
· Trauma
· Use or overdose of drugs, especially cocaine, amphetamines, statins, heroin, or PCP
A combination of signs and symptoms characterize compartment syndrome. The classic sign of acute compartment syndrome is pain, especially when the muscle is stretched.
· There may also be a tingling or burning sensation (paresthesias) in the muscle.
· The muscle may feel tight or full.
· If the area becomes numb or paralysis sets in, cell death has begun and efforts to lower the pressure in the compartment may not be successful in restoring function.